Mining potentially actionable kinase gene fusions in cancer cell lines with the KuNG FU database

Inhibition of kinase gene fusions (KGFs) has proven successful in cancer treatment and continues to represent an attractive research area, due to kinase druggability and clinical validation. Indeed, literature and public databases report a remarkable number of KGFs as potential drug targets, often i...

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Detalles Bibliográficos
Autores principales: Somaschini, Alessio, Di Bella, Sebastiano, Cusi, Carlo, Raddrizzani, Laura, Leone, Antonella, Carapezza, Giovanni, Mazza, Tommaso, Isacchi, Antonella, Bosotti, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705673/
https://www.ncbi.nlm.nih.gov/pubmed/33257674
http://dx.doi.org/10.1038/s41597-020-00761-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705673/
https://www.ncbi.nlm.nih.gov/pubmed/33257674
http://dx.doi.org/10.1038/s41597-020-00761-2

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