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Mining potentially actionable kinase gene fusions in cancer cell lines with the KuNG FU database
Inhibition of kinase gene fusions (KGFs) has proven successful in cancer treatment and continues to represent an attractive research area, due to kinase druggability and clinical validation. Indeed, literature and public databases report a remarkable number of KGFs as potential drug targets, often i...
Autores principales: | Somaschini, Alessio, Di Bella, Sebastiano, Cusi, Carlo, Raddrizzani, Laura, Leone, Antonella, Carapezza, Giovanni, Mazza, Tommaso, Isacchi, Antonella, Bosotti, Roberta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705673/ https://www.ncbi.nlm.nih.gov/pubmed/33257674 http://dx.doi.org/10.1038/s41597-020-00761-2 |
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