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High dose vitamin D(3) empowers effects of subcutaneous immunotherapy in a grass pollen-driven mouse model of asthma

Allergen-specific immunotherapy (AIT) has the potential to provide long-term protection against allergic diseases. However, efficacy of AIT is suboptimal, while application of high doses allergen has safety concerns. The use of adjuvants, like 1,25(OH)(2)VitD(3) (VitD3), can improve efficacy of AIT....

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Detalles Bibliográficos
Autores principales: Hesse, Laura, van Ieperen, N., Petersen, Arjen H., Elberink, J. N. G. Oude, van Oosterhout, Antoon J. M., Nawijn, Martijn C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705678/
https://www.ncbi.nlm.nih.gov/pubmed/33257771
http://dx.doi.org/10.1038/s41598-020-77947-6