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HIF1α activation in dendritic cells under sterile conditions promotes an anti-inflammatory phenotype through accumulation of intracellular lipids

Obesity is among the leading causes of elevated cardiovascular disease mortality and morbidity. Adipose tissue dysfunction, insulin resistance and inflammation are recognized as important risk factors for the development of cardiovascular disorders in obesity. Hypoxia appears to be a key factor in a...

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Detalles Bibliográficos
Autores principales: Wood, Elizabeth G., Macdougall, Claire E., Blythe, Hazel, Clément, Marc, Colas, Romain A., Dalli, Jesmond, Marelli-Berg, Federica, Longhi, M. Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705732/
https://www.ncbi.nlm.nih.gov/pubmed/33257753
http://dx.doi.org/10.1038/s41598-020-77793-6