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HIF1α activation in dendritic cells under sterile conditions promotes an anti-inflammatory phenotype through accumulation of intracellular lipids
Obesity is among the leading causes of elevated cardiovascular disease mortality and morbidity. Adipose tissue dysfunction, insulin resistance and inflammation are recognized as important risk factors for the development of cardiovascular disorders in obesity. Hypoxia appears to be a key factor in a...
Autores principales: | Wood, Elizabeth G., Macdougall, Claire E., Blythe, Hazel, Clément, Marc, Colas, Romain A., Dalli, Jesmond, Marelli-Berg, Federica, Longhi, M. Paula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705732/ https://www.ncbi.nlm.nih.gov/pubmed/33257753 http://dx.doi.org/10.1038/s41598-020-77793-6 |
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