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Development of a multi-antigenic SARS-CoV-2 vaccine candidate using a synthetic poxvirus platform

Modified Vaccinia Ankara (MVA) is a highly attenuated poxvirus vector that is widely used to develop vaccines for infectious diseases and cancer. We demonstrate the construction of a vaccine platform based on a unique three-plasmid system to efficiently generate recombinant MVA vectors from chemical...

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Detalles Bibliográficos
Autores principales: Chiuppesi, Flavia, Salazar, Marcela d’Alincourt, Contreras, Heidi, Nguyen, Vu H., Martinez, Joy, Park, Yoonsuh, Nguyen, Jenny, Kha, Mindy, Iniguez, Angelina, Zhou, Qiao, Kaltcheva, Teodora, Levytskyy, Roman, Ebelt, Nancy D., Kang, Tae Hyuk, Wu, Xiwei, Rogers, Thomas F., Manuel, Edwin R., Shostak, Yuriy, Diamond, Don J., Wussow, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705736/
https://www.ncbi.nlm.nih.gov/pubmed/33257686
http://dx.doi.org/10.1038/s41467-020-19819-1