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BETs inhibition attenuates oxidative stress and preserves muscle integrity in Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) affects 1 in 3500 live male births. To date, there is no effective cure for DMD, and the identification of novel molecular targets involved in disease progression is important to design more effective treatments and therapies to alleviate DMD symptoms. Here, we show...

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Detalles Bibliográficos
Autores principales: Segatto, Marco, Szokoll, Roberta, Fittipaldi, Raffaella, Bottino, Cinzia, Nevi, Lorenzo, Mamchaoui, Kamel, Filippakopoulos, Panagis, Caretti, Giuseppina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705749/
https://www.ncbi.nlm.nih.gov/pubmed/33257646
http://dx.doi.org/10.1038/s41467-020-19839-x