USP24 stabilizes bromodomain containing proteins to promote lung cancer malignancy

Bromodomain (BRD)-containing proteins are important for chromatin remodeling to regulate gene expression. In this study, we found that the deubiquitinase USP24 interacted with BRD through its C-terminus increased the levels of most BRD-containing proteins through increasing their protein stability b...

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Detalles Bibliográficos
Autores principales: Wang, Shao-An, Young, Ming-Jer, Jeng, Wen-Yih, Liu, Chia-Yu, Hung, Jan-Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705756/
https://www.ncbi.nlm.nih.gov/pubmed/33257797
http://dx.doi.org/10.1038/s41598-020-78000-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705756/
https://www.ncbi.nlm.nih.gov/pubmed/33257797
http://dx.doi.org/10.1038/s41598-020-78000-2

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