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USP24 stabilizes bromodomain containing proteins to promote lung cancer malignancy
Bromodomain (BRD)-containing proteins are important for chromatin remodeling to regulate gene expression. In this study, we found that the deubiquitinase USP24 interacted with BRD through its C-terminus increased the levels of most BRD-containing proteins through increasing their protein stability b...
Autores principales: | Wang, Shao-An, Young, Ming-Jer, Jeng, Wen-Yih, Liu, Chia-Yu, Hung, Jan-Jong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705756/ https://www.ncbi.nlm.nih.gov/pubmed/33257797 http://dx.doi.org/10.1038/s41598-020-78000-2 |
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