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Generation of universal and hypoimmunogenic human pluripotent stem cells

There is a need to store very large numbers of conventional human pluripotent stem cell (hPSC) lines for their off‐the‐shelf usage in stem cell therapy. Therefore, it is valuable to generate “universal” or “hypoimmunogenic” hPSCs with gene‐editing technology by knocking out or in immune‐related gene...

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Detalles Bibliográficos
Autores principales: Ye, Qingsong, Sung, Tzu‐Cheng, Yang, Jen‐Ming, Ling, Qing‐Dong, He, Yan, Higuchi, Akon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705897/
https://www.ncbi.nlm.nih.gov/pubmed/33174655
http://dx.doi.org/10.1111/cpr.12946