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Peptide Inhibitors of the α-Cobratoxin–Nicotinic Acetylcholine Receptor Interaction

[Image: see text] Venomous snakebites cause >100 000 deaths every year, in many cases via potent depression of human neuromuscular signaling by snake α-neurotoxins. Emergency therapy still relies on antibody-based antivenom, hampered by poor access, frequent adverse reactions, and cumbersome prod...

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Detalles Bibliográficos
Autores principales: Lynagh, Timothy, Kiontke, Stephan, Meyhoff-Madsen, Maria, Gless, Bengt H., Johannesen, Jónas, Kattelmann, Sabrina, Christiansen, Anders, Dufva, Martin, Laustsen, Andreas H., Devkota, Kanchan, Olsen, Christian A., Kümmel, Daniel, Pless, Stephan Alexander, Lohse, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705965/
https://www.ncbi.nlm.nih.gov/pubmed/33143415
http://dx.doi.org/10.1021/acs.jmedchem.0c01202