Hyperoxia sensitizes hypoxic HeLa cells to ionizing radiation by downregulating HIF-1α and VEGF expression

The current study investigated whether hyperoxia may reverse hypoxia-induced radioresistance (RR) in cervical cancer. Human HeLa cells exposed to hypoxic, normoxic or hyperoxic conditions were irradiated using X-rays. Cell proliferation and apoptosis were analyzed using MTT assays and flow cytometry...

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Detalles Bibliográficos
Autores principales: Dong, Dan, Fu, Yan, Chen, Feng, Zhang, Jing, Jia, Haiyan, Li, Jia, Wang, Huailin, Wen, Jihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706008/
https://www.ncbi.nlm.nih.gov/pubmed/33215223
http://dx.doi.org/10.3892/mmr.2020.11700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706008/
https://www.ncbi.nlm.nih.gov/pubmed/33215223
http://dx.doi.org/10.3892/mmr.2020.11700

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