Down syndrome cell adhesion molecule like-1 (DSCAML1) links the GABA system and seizure susceptibility

The Ihara epileptic rat (IER) is a mutant model with limbic-like seizures whose pathology and causative gene remain elusive. In this report, via linkage analysis, we identified Down syndrome cell adhesion molecule-like 1(Dscaml1) as the responsible gene for IER. A single base mutation in Dscaml1 cau...

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Detalles Bibliográficos
Autores principales: Hayase, Yoneko, Amano, Shigeru, Hashizume, Koichi, Tominaga, Takashi, Miyamoto, Hiroyuki, Kanno, Yukie, Ueno-Inoue, Yukiko, Inoue, Takayoshi, Yamada, Mayumi, Ogata, Shigehiro, Balan, Shabeesh, Hayashi, Ken, Miura, Yoshiki, Tokudome, Kentaro, Ohno, Yukihiro, Nishijo, Takuma, Momiyama, Toshihiko, Yanagawa, Yuchio, Takizawa, Akiko, Mashimo, Tomoji, Serikawa, Tadao, Sekine, Akihiro, Nakagawa, Eiji, Takeshita, Eri, Yoshikawa, Takeo, Waga, Chikako, Inoue, Ken, Goto, Yu-ichi, Nabeshima, Yoichi, Ihara, Nobuo, Yamakawa, Kazuhiro, Taya, Shinichiro, Hoshino, Mikio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706048/
https://www.ncbi.nlm.nih.gov/pubmed/33256836
http://dx.doi.org/10.1186/s40478-020-01082-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706048/
https://www.ncbi.nlm.nih.gov/pubmed/33256836
http://dx.doi.org/10.1186/s40478-020-01082-6

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