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Long noncoding RNA MEG3 blocks telomerase activity in human liver cancer stem cells epigenetically
BACKGROUND: MEG3 downregulated the expression in several tumors and inhibits human tumorigenesis. But so far, the mechanism of MEG3 in tumorigenesis is still unclear. METHODS: In gene infection, cellular and molecular technologies and tumorigenesis test in vitro and in vivo were performed, respectiv...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706068/ https://www.ncbi.nlm.nih.gov/pubmed/33256840 http://dx.doi.org/10.1186/s13287-020-02036-4 |