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Long noncoding RNA MEG3 blocks telomerase activity in human liver cancer stem cells epigenetically

BACKGROUND: MEG3 downregulated the expression in several tumors and inhibits human tumorigenesis. But so far, the mechanism of MEG3 in tumorigenesis is still unclear. METHODS: In gene infection, cellular and molecular technologies and tumorigenesis test in vitro and in vivo were performed, respectiv...

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Detalles Bibliográficos
Autores principales:	Jiang, Xiaoxue, Wang, Liyan, Xie, Sijie, Chen, Yingjie, Song, Shuting, Lu, Yanan, Lu, Dongdong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706068/ https://www.ncbi.nlm.nih.gov/pubmed/33256840 http://dx.doi.org/10.1186/s13287-020-02036-4

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