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Unconventional Macrocyclizations in Natural Product Synthesis
[Image: see text] Over the past several decades, macrocyclic compounds have emerged as increasingly significant therapeutic candidates in drug discovery. Their pharmacological activity hinges on their rotationally restricted three-dimensional orientation, resulting in a unique conformational preorga...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706100/ https://www.ncbi.nlm.nih.gov/pubmed/33274267 http://dx.doi.org/10.1021/acscentsci.0c00599 |