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Serum surfactant protein D as a predictive biomarker for the efficacy of pirfenidone in patients with idiopathic pulmonary fibrosis: a post-hoc analysis of the phase 3 trial in Japan

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a progressive, fatal disorder with a variable disease course. The recent advancement of antifibrotic therapy has increased the need for reliable and specific biomarkers. This study aimed to assess alveolar epithelial biomarkers as predictors for the...

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Detalles Bibliográficos
Autores principales: Ikeda, Kimiyuki, Chiba, Hirofumi, Nishikiori, Hirotaka, Azuma, Arata, Kondoh, Yasuhiro, Ogura, Takashi, Taguchi, Yoshio, Ebina, Masahito, Sakaguchi, Hiroki, Miyazawa, Shogo, Suga, Moritaka, Sugiyama, Yukihiko, Nukiwa, Toshihiro, Kudoh, Shoji, Takahashi, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706186/
https://www.ncbi.nlm.nih.gov/pubmed/33256760
http://dx.doi.org/10.1186/s12931-020-01582-y