Cargando…
Altered striatal dopamine levels in Parkinson’s disease VPS35 D620N mutant transgenic aged mice
Vacuolar protein sorting 35 (VPS35) is a major component of the retromer complex that mediates the retrograde transport of cargo proteins from endosomes to the trans-Golgi network. Mutations such as D620N in the VPS35 gene have been identified in patients with autosomal dominant Parkinson’s disease...
Autores principales: | , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706192/ https://www.ncbi.nlm.nih.gov/pubmed/33261640 http://dx.doi.org/10.1186/s13041-020-00704-3 |