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Altered striatal dopamine levels in Parkinson’s disease VPS35 D620N mutant transgenic aged mice
Vacuolar protein sorting 35 (VPS35) is a major component of the retromer complex that mediates the retrograde transport of cargo proteins from endosomes to the trans-Golgi network. Mutations such as D620N in the VPS35 gene have been identified in patients with autosomal dominant Parkinson’s disease...
Autores principales: | Vanan, Sarivin, Zeng, Xiaoxia, Chia, Sook Yoong, Varnäs, Katarina, Jiang, Mei, Zhang, Ke, Saw, Wuan Ting, Padmanabhan, Parasuraman, Yu, Wei-Ping, Zhou, Zhi-Dong, Halldin, Christer, Gulyás, Balázs, Tan, Eng-King, Zeng, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706192/ https://www.ncbi.nlm.nih.gov/pubmed/33261640 http://dx.doi.org/10.1186/s13041-020-00704-3 |
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