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Eltrombopag inhibits the proliferation of Ewing sarcoma cells via iron chelation and impaired DNA replication
BACKGROUND: The treatment of Ewing sarcoma, an aggressive bone and soft tissue sarcoma, is associated with suboptimal outcomes and significant side-effects. Consequently, there is an urgent need to identify novel therapies that will improve outcomes for children and adults with Ewing sarcoma tumors...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706234/ https://www.ncbi.nlm.nih.gov/pubmed/33256675 http://dx.doi.org/10.1186/s12885-020-07668-6 |