Eltrombopag inhibits the proliferation of Ewing sarcoma cells via iron chelation and impaired DNA replication

BACKGROUND: The treatment of Ewing sarcoma, an aggressive bone and soft tissue sarcoma, is associated with suboptimal outcomes and significant side-effects. Consequently, there is an urgent need to identify novel therapies that will improve outcomes for children and adults with Ewing sarcoma tumors...

Descripción completa

Detalles Bibliográficos
Autores principales: Waters, Torin, Goss, Kelli L., Koppenhafer, Stacia L., Terry, William W., Gordon, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706234/
https://www.ncbi.nlm.nih.gov/pubmed/33256675
http://dx.doi.org/10.1186/s12885-020-07668-6

Ejemplares similares

Ejemplares similares