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Highly diversified core promoters in the human genome and their effects on gene expression and disease predisposition

BACKGROUND: Core promoter controls transcription initiation. However, little is known for core promoter diversity in the human genome and its relationship with diseases. We hypothesized that as a functional important component in the genome, the core promoter in the human genome could be under evolu...

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Detalles Bibliográficos
Autores principales: Gupta, Hemant, Chandratre, Khyati, Sinha, Siddharth, Huang, Teng, Wu, Xiaobing, Cui, Jian, Zhang, Michael Q., Wang, San Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706239/
https://www.ncbi.nlm.nih.gov/pubmed/33256598
http://dx.doi.org/10.1186/s12864-020-07222-5