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Highly diversified core promoters in the human genome and their effects on gene expression and disease predisposition
BACKGROUND: Core promoter controls transcription initiation. However, little is known for core promoter diversity in the human genome and its relationship with diseases. We hypothesized that as a functional important component in the genome, the core promoter in the human genome could be under evolu...
Autores principales: | Gupta, Hemant, Chandratre, Khyati, Sinha, Siddharth, Huang, Teng, Wu, Xiaobing, Cui, Jian, Zhang, Michael Q., Wang, San Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706239/ https://www.ncbi.nlm.nih.gov/pubmed/33256598 http://dx.doi.org/10.1186/s12864-020-07222-5 |
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