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Glioblastoma stem cells induce quiescence in surrounding neural stem cells via Notch signaling

There is increasing evidence demonstrating that adult neural stem cells (NSCs) are a cell of origin of glioblastoma. Here we analyzed the interaction between transformed and wild-type NSCs isolated from the adult mouse subventricular zone niche. We found that transformed NSCs are refractory to quies...

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Detalles Bibliográficos
Autores principales: Lawlor, Katerina, Marques-Torrejon, Maria Angeles, Dharmalingham, Gopuraja, El-Azhar, Yasmine, Schneider, Michael D., Pollard, Steven M., Rodríguez, Tristan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706704/
https://www.ncbi.nlm.nih.gov/pubmed/33184225
http://dx.doi.org/10.1101/gad.336917.120