Sexually dimorphic DNA damage responses and mutation avoidance in the mouse germline

Germ cells specified during fetal development form the foundation of the mammalian germline. These primordial germ cells (PGCs) undergo rapid proliferation, yet the germline is highly refractory to mutation accumulation compared with somatic cells. Importantly, while the presence of endogenous or ex...

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Detalles Bibliográficos
Autores principales: Bloom, Jordana C., Schimenti, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706705/
https://www.ncbi.nlm.nih.gov/pubmed/33184219
http://dx.doi.org/10.1101/gad.341602.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706705/
https://www.ncbi.nlm.nih.gov/pubmed/33184219
http://dx.doi.org/10.1101/gad.341602.120

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