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Sexually dimorphic DNA damage responses and mutation avoidance in the mouse germline
Germ cells specified during fetal development form the foundation of the mammalian germline. These primordial germ cells (PGCs) undergo rapid proliferation, yet the germline is highly refractory to mutation accumulation compared with somatic cells. Importantly, while the presence of endogenous or ex...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706705/ https://www.ncbi.nlm.nih.gov/pubmed/33184219 http://dx.doi.org/10.1101/gad.341602.120 |