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Cross-species analysis of enhancer logic using deep learning

Deciphering the genomic regulatory code of enhancers is a key challenge in biology because this code underlies cellular identity. A better understanding of how enhancers work will improve the interpretation of noncoding genome variation and empower the generation of cell type–specific drivers for ge...

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Detalles Bibliográficos
Autores principales: Minnoye, Liesbeth, Taskiran, Ibrahim Ihsan, Mauduit, David, Fazio, Maurizio, Van Aerschot, Linde, Hulselmans, Gert, Christiaens, Valerie, Makhzami, Samira, Seltenhammer, Monika, Karras, Panagiotis, Primot, Aline, Cadieu, Edouard, van Rooijen, Ellen, Marine, Jean-Christophe, Egidy, Giorgia, Ghanem, Ghanem-Elias, Zon, Leonard, Wouters, Jasper, Aerts, Stein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706731/
https://www.ncbi.nlm.nih.gov/pubmed/32732264
http://dx.doi.org/10.1101/gr.260844.120