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Cross-species analysis of enhancer logic using deep learning
Deciphering the genomic regulatory code of enhancers is a key challenge in biology because this code underlies cellular identity. A better understanding of how enhancers work will improve the interpretation of noncoding genome variation and empower the generation of cell type–specific drivers for ge...
Autores principales: | Minnoye, Liesbeth, Taskiran, Ibrahim Ihsan, Mauduit, David, Fazio, Maurizio, Van Aerschot, Linde, Hulselmans, Gert, Christiaens, Valerie, Makhzami, Samira, Seltenhammer, Monika, Karras, Panagiotis, Primot, Aline, Cadieu, Edouard, van Rooijen, Ellen, Marine, Jean-Christophe, Egidy, Giorgia, Ghanem, Ghanem-Elias, Zon, Leonard, Wouters, Jasper, Aerts, Stein |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706731/ https://www.ncbi.nlm.nih.gov/pubmed/32732264 http://dx.doi.org/10.1101/gr.260844.120 |
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