The crystal structure of mouse IRG1 suggests that cis-aconitate decarboxylase has an open and closed conformation

Itaconate, produced as an offshoot of the TCA cycle, is a multifunctional immunometabolite possessing antibacterial, antiviral, immune regulation, and tumor progression activities. The production of itaconate in biological systems is catalyzed by cis-aconitate decarboxylase (CAD, also known as immun...

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Detalles Bibliográficos
Autores principales: Chun, Hye Lin, Lee, So Yeon, Kim, Ki-Hwa, Lee, Chang Sup, Oh, Tae-Jin, Park, Hyun Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7707506/
https://www.ncbi.nlm.nih.gov/pubmed/33259501
http://dx.doi.org/10.1371/journal.pone.0242383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7707506/
https://www.ncbi.nlm.nih.gov/pubmed/33259501
http://dx.doi.org/10.1371/journal.pone.0242383

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