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3D in situ imaging of the female reproductive tract reveals molecular signatures of fertilizing spermatozoa in mice

Out of millions of ejaculated sperm, a few reach the fertilization site in mammals. Flagellar Ca(2+) signaling nanodomains, organized by multi-subunit CatSper calcium channel complexes, are pivotal for sperm migration in the female tract, implicating CatSper-dependent mechanisms in sperm selection....

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Detalles Bibliográficos
Autores principales: Ded, Lukas, Hwang, Jae Yeon, Miki, Kiyoshi, Shi, Huanan F, Chung, Jean-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7707823/
https://www.ncbi.nlm.nih.gov/pubmed/33078708
http://dx.doi.org/10.7554/eLife.62043