Clinical guidelines for burosumab in the treatment of XLH in children and adolescents: British paediatric and adolescent bone group recommendations

X-linked hypophosphataemia (XLH) is caused by a pathogenic variant in the PHEX gene, which leads to elevated circulating FGF23. High FGF23 causes hypophosphataemia, reduced active vitamin D concentration and clinically manifests as rickets in children and osteomalacia in children and adults. Convent...

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Detalles Bibliográficos
Autores principales: Padidela, Raja, Cheung, Moira S, Saraff, Vrinda, Dharmaraj, Poonam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7707830/
https://www.ncbi.nlm.nih.gov/pubmed/33112809
http://dx.doi.org/10.1530/EC-20-0291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7707830/
https://www.ncbi.nlm.nih.gov/pubmed/33112809
http://dx.doi.org/10.1530/EC-20-0291

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