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Simultaneous quantification of mRNA and protein in single cells reveals post-transcriptional effects of genetic variation
Trans-acting DNA variants may specifically affect mRNA or protein levels of genes located throughout the genome. However, prior work compared trans-acting loci mapped in separate studies, many of which had limited statistical power. Here, we developed a CRISPR-based system for simultaneous quantific...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7707838/ https://www.ncbi.nlm.nih.gov/pubmed/33191917 http://dx.doi.org/10.7554/eLife.60645 |