An adjunctive therapy administered with an antibiotic prevents enrichment of antibiotic-resistant clones of a colonizing opportunistic pathogen

A key challenge in antibiotic stewardship is figuring out how to use antibiotics therapeutically without promoting the evolution of antibiotic resistance. Here, we demonstrate proof of concept for an adjunctive therapy that allows intravenous antibiotic treatment without driving the evolution and on...

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Detalles Bibliográficos
Autores principales: Morley, Valerie J, Kinnear, Clare L, Sim, Derek G, Olson, Samantha N, Jackson, Lindsey M, Hansen, Elsa, Usher, Grace A, Showalter, Scott A, Pai, Manjunath P, Woods, Robert J, Read, Andrew F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7707840/
https://www.ncbi.nlm.nih.gov/pubmed/33258450
http://dx.doi.org/10.7554/eLife.58147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7707840/
https://www.ncbi.nlm.nih.gov/pubmed/33258450
http://dx.doi.org/10.7554/eLife.58147

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