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RNA as the stone guest of protein aggregation

The study of prions as infectious aggregates dates several decades. From its original formulation, the definition of a prion has progressively changed to the point that many aggregation-prone proteins are now considered bona fide prions. RNA molecules, not included in the original ‘protein-only hypo...

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Detalles Bibliográficos
Autores principales: Louka, Alexandra, Zacco, Elsa, Temussi, Piero Andrea, Tartaglia, Gian Gaetano, Pastore, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708036/
https://www.ncbi.nlm.nih.gov/pubmed/33068411
http://dx.doi.org/10.1093/nar/gkaa822