G-quadruplex–R-loop interactions and the mechanism of anticancer G-quadruplex binders

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Genomic DNA and cellular RNAs can form a variety of non-B secondary structures, including G-quadruplex (G4) and R-loops. G4s are constituted by stacked guanine tetrads held together by Hoogsteen hydrogen bonds and can form at key regulatory sites of eukaryote genomes and transcripts, including gene...

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Detalles Bibliográficos
Autores principales: Miglietta, Giulia, Russo, Marco, Capranico, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Survey and Summary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708042/
https://www.ncbi.nlm.nih.gov/pubmed/33137181
http://dx.doi.org/10.1093/nar/gkaa944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708042/
https://www.ncbi.nlm.nih.gov/pubmed/33137181
http://dx.doi.org/10.1093/nar/gkaa944

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