Novel ribonucleotide discrimination in the RNA polymerase-like two-barrel catalytic core of Family D DNA polymerases

Family D DNA polymerase (PolD) is the essential replicative DNA polymerase for duplication of most archaeal genomes. PolD contains a unique two-barrel catalytic core absent from all other DNA polymerase families but found in RNA polymerases (RNAPs). While PolD has an ancestral RNA polymerase catalyt...

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Detalles Bibliográficos
Autores principales: Zatopek, Kelly M, Alpaslan, Ece, Evans, Thomas C, Sauguet, Ludovic, Gardner, Andrew F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708050/
https://www.ncbi.nlm.nih.gov/pubmed/33137176
http://dx.doi.org/10.1093/nar/gkaa986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708050/
https://www.ncbi.nlm.nih.gov/pubmed/33137176
http://dx.doi.org/10.1093/nar/gkaa986

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