2′-O-Methylation can increase the abundance and lifetime of alternative RNA conformational states

2′-O-Methyl (Nm) is a highly abundant post-transcriptional RNA modification that plays important biological roles through mechanisms that are not entirely understood. There is evidence that Nm can alter the biological activities of RNAs by biasing the ribose sugar pucker equilibrium toward the C3′-e...

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Detalles Bibliográficos
Autores principales: Abou Assi, Hala, Rangadurai, Atul K, Shi, Honglue, Liu, Bei, Clay, Mary C, Erharter, Kevin, Kreutz, Christoph, Holley, Christopher L, Al-Hashimi, Hashim M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708057/
https://www.ncbi.nlm.nih.gov/pubmed/33104789
http://dx.doi.org/10.1093/nar/gkaa928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708057/
https://www.ncbi.nlm.nih.gov/pubmed/33104789
http://dx.doi.org/10.1093/nar/gkaa928

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