INDEL detection, the ‘Achilles heel’ of precise genome editing: a survey of methods for accurate profiling of gene editing induced indels

Advances in genome editing technologies have enabled manipulation of genomes at the single base level. These technologies are based on programmable nucleases (PNs) that include meganucleases, zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs) and Clustered Regular...

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Detalles Bibliográficos
Autores principales: Bennett, Eric Paul, Petersen, Bent Larsen, Johansen, Ida Elisabeth, Niu, Yiyuan, Yang, Zhang, Chamberlain, Christopher Aled, Met, Özcan, Wandall, Hans H, Frödin, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Survey and Summary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708060/
https://www.ncbi.nlm.nih.gov/pubmed/33170255
http://dx.doi.org/10.1093/nar/gkaa975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708060/
https://www.ncbi.nlm.nih.gov/pubmed/33170255
http://dx.doi.org/10.1093/nar/gkaa975

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