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The catalytic activity of the translation termination factor methyltransferase Mtq2-Trm112 complex is required for large ribosomal subunit biogenesis

The Mtq2-Trm112 methyltransferase modifies the eukaryotic translation termination factor eRF1 on the glutamine side chain of a universally conserved GGQ motif that is essential for release of newly synthesized peptides. Although this modification is found in the three domains of life, its exact role...

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Detalles Bibliográficos
Autores principales: Lacoux, Caroline, Wacheul, Ludivine, Saraf, Kritika, Pythoud, Nicolas, Huvelle, Emmeline, Figaro, Sabine, Graille, Marc, Carapito, Christine, Lafontaine, Denis L J, Heurgué-Hamard, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708063/
https://www.ncbi.nlm.nih.gov/pubmed/33166396
http://dx.doi.org/10.1093/nar/gkaa972