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The catalytic activity of the translation termination factor methyltransferase Mtq2-Trm112 complex is required for large ribosomal subunit biogenesis
The Mtq2-Trm112 methyltransferase modifies the eukaryotic translation termination factor eRF1 on the glutamine side chain of a universally conserved GGQ motif that is essential for release of newly synthesized peptides. Although this modification is found in the three domains of life, its exact role...
Autores principales: | Lacoux, Caroline, Wacheul, Ludivine, Saraf, Kritika, Pythoud, Nicolas, Huvelle, Emmeline, Figaro, Sabine, Graille, Marc, Carapito, Christine, Lafontaine, Denis L J, Heurgué-Hamard, Valérie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708063/ https://www.ncbi.nlm.nih.gov/pubmed/33166396 http://dx.doi.org/10.1093/nar/gkaa972 |
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