A role for LSH in facilitating DNA methylation by DNMT1 through enhancing UHRF1 chromatin association

LSH, a SNF2 family DNA helicase, is a key regulator of DNA methylation in mammals. How LSH facilitates DNA methylation is not well defined. While previous studies with mouse embryonic stem cells (mESc) and fibroblasts (MEFs) derived from Lsh knockout mice have revealed a role of Lsh in de novo DNA m...

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Detalles Bibliográficos
Autores principales: Han, Mengmeng, Li, Jialun, Cao, Yaqiang, Huang, Yuanyong, Li, Wen, Zhu, Haijun, Zhao, Qian, Han, Jing-Dong Jackie, Wu, Qihan, Li, Jiwen, Feng, Jing, Wong, Jiemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708066/
https://www.ncbi.nlm.nih.gov/pubmed/33170271
http://dx.doi.org/10.1093/nar/gkaa1003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708066/
https://www.ncbi.nlm.nih.gov/pubmed/33170271
http://dx.doi.org/10.1093/nar/gkaa1003

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