On the interaction of an anticancer trisubstituted naphthalene diimide with G-quadruplexes of different topologies: a structural insight

Naphthalene diimides showed significant anticancer activity in animal models, with therapeutic potential related to their ability to strongly interact with G-quadruplexes. Recently, a trifunctionalized naphthalene diimide, named NDI-5, was identified as the best analogue of a mini-library of novel n...

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Detalles Bibliográficos
Autores principales: Platella, Chiara, Trajkovski, Marko, Doria, Filippo, Freccero, Mauro, Plavec, Janez, Montesarchio, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708068/
https://www.ncbi.nlm.nih.gov/pubmed/33170272
http://dx.doi.org/10.1093/nar/gkaa1001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708068/
https://www.ncbi.nlm.nih.gov/pubmed/33170272
http://dx.doi.org/10.1093/nar/gkaa1001

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