Improved nearest-neighbor parameters for the stability of RNA/DNA hybrids under a physiological condition

The stability of Watson–Crick paired RNA/DNA hybrids is important for designing optimal oligonucleotides for ASO (Antisense Oligonucleotide) and CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)–Cas9 techniques. Previous nearest-neighbour (NN) parameters for predicting hybrid stabil...

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Detalles Bibliográficos
Autores principales: Banerjee, Dipanwita, Tateishi-Karimata, Hisae, Ohyama, Tatsuya, Ghosh, Saptarshi, Endoh, Tamaki, Takahashi, Shuntaro, Sugimoto, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Data Resources and Analyses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708073/
https://www.ncbi.nlm.nih.gov/pubmed/32663294
http://dx.doi.org/10.1093/nar/gkaa572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708073/
https://www.ncbi.nlm.nih.gov/pubmed/32663294
http://dx.doi.org/10.1093/nar/gkaa572

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