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Improved nearest-neighbor parameters for the stability of RNA/DNA hybrids under a physiological condition

The stability of Watson–Crick paired RNA/DNA hybrids is important for designing optimal oligonucleotides for ASO (Antisense Oligonucleotide) and CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)–Cas9 techniques. Previous nearest-neighbour (NN) parameters for predicting hybrid stabil...

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Detalles Bibliográficos
Autores principales:	Banerjee, Dipanwita, Tateishi-Karimata, Hisae, Ohyama, Tatsuya, Ghosh, Saptarshi, Endoh, Tamaki, Takahashi, Shuntaro, Sugimoto, Naoki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Data Resources and Analyses
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708073/ https://www.ncbi.nlm.nih.gov/pubmed/32663294 http://dx.doi.org/10.1093/nar/gkaa572

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