Loss of miR-192-5p initiates a hyperglycolysis and stemness positive feedback in hepatocellular carcinoma

BACKGROUND: Emerging studies revealed that cancer stem cells (CSCs) possessed peculiar metabolic properties, which however remained largely unknown in hepatocellular carcinoma (HCC). Genetic silencing of liver-abundant miR-192-5p was a key feature for multiple groups of CSC-positive HCCs. We thus ai...

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Detalles Bibliográficos
Autores principales: Gu, Yuanzhuo, Ji, Fubo, Liu, Niya, Zhao, Yongzhi, Wei, Xiyang, Hu, Shiyuan, Jia, Wei, Wang, Xin Wei, Budhu, Anuradha, Ji, Juling, Zhao, Bin, Roessler, Stephanie, Zheng, Xin, Ji, Junfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708108/
https://www.ncbi.nlm.nih.gov/pubmed/33256802
http://dx.doi.org/10.1186/s13046-020-01785-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708108/
https://www.ncbi.nlm.nih.gov/pubmed/33256802
http://dx.doi.org/10.1186/s13046-020-01785-7

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