FFAR1 activation attenuates histamine-induced myosin light chain phosphorylation and cortical tension development in human airway smooth muscle cells

BACKGROUND: Activation of free fatty acid receptors (FFAR1 and FFAR4) which are G protein-coupled receptors (GPCRs) with established (patho)physiological roles in a variety of obesity-related disorders, induce human airway smooth muscle (HASM) cell proliferation and shortening. We reported amplified...

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Detalles Bibliográficos
Autores principales: Xu, Shengjie, Schwab, Anthony, Karmacharya, Nikhil, Cao, Gaoyuan, Woo, Joanna, Kim, Nicholas, An, Steven S., Panettieri Jr, Reynold A., Jude, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708129/
https://www.ncbi.nlm.nih.gov/pubmed/33256729
http://dx.doi.org/10.1186/s12931-020-01584-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708129/
https://www.ncbi.nlm.nih.gov/pubmed/33256729
http://dx.doi.org/10.1186/s12931-020-01584-w

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