Cargando…

KLHL17/Actinfilin, a brain-specific gene associated with infantile spasms and autism, regulates dendritic spine enlargement

BACKGROUND: Dendritic spines, the actin-rich protrusions emerging from dendrites, are the subcellular locations of excitatory synapses in the mammalian brain. Many actin-regulating molecules modulate dendritic spine morphology. Since dendritic spines are neuron-specific structures, it is reasonable...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Hsiao-Tang, Huang, Tzyy-Nan, Hsueh, Yi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708131/
https://www.ncbi.nlm.nih.gov/pubmed/33256713
http://dx.doi.org/10.1186/s12929-020-00696-1