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Finding a suitable library size to call variants in RNA-Seq

BACKGROUND: RNA sequencing allows the study of both gene expression changes and transcribed mutations, providing a highly effective way to gain insight into cancer biology. When planning the sequencing of a large cohort of samples, library size is a fundamental factor affecting both the overall cost...

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Detalles Bibliográficos
Autores principales: Quaglieri, Anna, Flensburg, Christoffer, Speed, Terence P., Majewski, Ian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708150/
https://www.ncbi.nlm.nih.gov/pubmed/33261552
http://dx.doi.org/10.1186/s12859-020-03860-4