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Finding a suitable library size to call variants in RNA-Seq
BACKGROUND: RNA sequencing allows the study of both gene expression changes and transcribed mutations, providing a highly effective way to gain insight into cancer biology. When planning the sequencing of a large cohort of samples, library size is a fundamental factor affecting both the overall cost...
Autores principales: | Quaglieri, Anna, Flensburg, Christoffer, Speed, Terence P., Majewski, Ian J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708150/ https://www.ncbi.nlm.nih.gov/pubmed/33261552 http://dx.doi.org/10.1186/s12859-020-03860-4 |
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