A novel computational strategy for DNA methylation imputation using mixture regression model (MRM)

BACKGROUND: DNA methylation is an important heritable epigenetic mark that plays a crucial role in transcriptional regulation and the pathogenesis of various human disorders. The commonly used DNA methylation measurement approaches, e.g., Illumina Infinium HumanMethylation-27 and -450 BeadChip array...

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Detalles Bibliográficos
Autores principales: Yu, Fangtang, Xu, Chao, Deng, Hong-Wen, Shen, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708217/
https://www.ncbi.nlm.nih.gov/pubmed/33261550
http://dx.doi.org/10.1186/s12859-020-03865-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708217/
https://www.ncbi.nlm.nih.gov/pubmed/33261550
http://dx.doi.org/10.1186/s12859-020-03865-z

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